Prevalence of Chronic Obstructive Pulmonary Disease (COPD) Among Patients Successfully Treated for Pulmonary Tuberculosis in Ethiopia.

Authors

  • Amsalu Bekele AAU
  • Meron Getachew
  • Charles B. Sherman
  • Neil W. Schluger

Abstract

 

COPD is currently the fourth leading cause of death in the world. In 2012, ≥ 3 million people died of COPD, accounting for 6% of all deaths globally. Pulmonary tuberculosis is emerging as a potential risk factor in the pathogenesis and severity of COPD. The object of this study was to evaluate the prevalence of COPD in patients successfully treated for PTB seen at Tikur Anbessa Specialized Hospital, in Ethiopia.

Methodology: We conducted a cross-sectional study of patients > 15 years of age who were successfully treated for PTB and followed in the Chest Unit at TASH from August 2016 to September 2017.  All patient had lung function measured using a Diagnostic EasyOne Plus model 2001 SN spirometer. Spirometric acceptability and reproducibility were determined using the published criteria of the ERS/ATS. A diagnosis of COPD was based on a post-bronchodilator FEV1/FVC<70% as recommended by the GOLD guidelines.

Results: A total of 99 patients were included in the analysis. 56% were male; the mean age of the group was 42.7 years. Forty-one of 99 (41.4%) study participants had post-bronchodilator FEV1/FVC<70%, meeting the study criteria for COPD. This percent was approximately 8 times higher than the 5% previously determined for COPD in the general population for subsaharan Africa. The majority of diagnosed COPD cases in our study had moderate to severe GOLD stage disease. 

Conclusions: The prevalence of COPD is high in our patients who were successfully treated for PTB and they should be strongly considered for screening and possible treatment

 

 

 

 

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Published

2020-03-19